21c Museum Hotel Durham

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About 21c Museum Hotel Durham

Art museum meets boutique hotel at 21c Museum Hotel in Durham, North Carolina. This multi-venue masterpiece houses not only an art-filled exhibition space and a full-service hotel, 21c also boasts one of the city's most desirable spas. And whether you’re a cultural connoisseur, foodie or sports enthusiast, one thing’s for sure: you’re going to fall in love with this historical charmer of a hotel. Durham is an incubator for vibrant arts and culinary communities. Because a stay here is more than just an ordinary hotel stay.

  • Durham, North Carolina

  • Boutique Hotel


What We Love

Prefer to be pampered? Let the skilled massage therapists ease those aching muscles, reawaken your senses and soothe away your stress. Choose from deep tissue, reflexology, hot river stone or aromatherapy massage sessions. Treatment rooms are conveniently located just a short elevator ride from your guest room, adjacent to the sauna, steam room and state-of-the-art fitness center. You don't have to venture far for a bit of indulgence. 

21c Museum Hotel Durham

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21c Museum Hotel Durham-Lounge _ Entrance.jpg


The 125 guest rooms and suites are spacious with high ceilings, large windows and custom furnishings, providing a respite to the stimulating and active museum spaces below. With all the comforts of home, the intention is to help you feel refreshed, restored and ready to explore North Carolina’s Triangle. Pet friendly rooms are also available.

Features & Amenities

  • Complimentary Wi-Fi
  • 42″ HDTV television
  • Alarm clock & docking station
  • Malin + Goetz bath amenities
  • Luxurious bedding
  • Original artwork


21c Museum Hotel Durham is located in Durham, North Carolina. The nearest airport is Raleigh-Durham International Airport (RDU).