21c Museum Hotel Cincinnati

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About 21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati is a cultural blast that doubles as a contemporary art museum. But the artistic fun doesn't stop there. The on-site art galleries are open all day, every day! Plus, there's a gift shop, a relaxing spa and a 24-hour gym to keep you feeling your best. And the cherry on top? A delicious eatery with dishes cooked up using a custom-built wood-burning fireplace and a rooftop cocktail terrace that boasts stunning views of the city skyline.

  • Cincinnati, Ohio

  • Luxury Boutique Hotel


What We Love

Treat yourself to some much-needed R&R at The Spa at 21c. With three tranquil treatment rooms and a menu full of options, you're sure to find the perfect way to unwind. From signature facials to relaxing massages and rejuvenating body wraps, you're in for a real treat! Food, art, culture, everything in between? Just a stone's throw from the dynamic heart of downtown Cincinnati, 21c makes for an ideal home base for any Queen City adventure. 

21c Museum Hotel Cincinnati

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The 156 stylish and artful guest rooms are filled with custom furnishings that lend a decidedly residential feel, providing a comfortable respite from the thought-provoking art and nonstop energy that fills the museum galleries.

Features & Amenities

  • Complimentary Wi-Fi
  • Alarm clock/docking station
  • Malin+Goetz bath amenities
  • Luxurious bedding
  • Custom tile 
  • Original artwork by Laura Lee Brown
  • Laundry service
  • Valet service


21c Museum Hotel Cincinnati is located in Cincinnati, Ohio.